alyaza [they/she]@beehaw.orgM to Science@beehaw.orgEnglish · 11 months agoResearchers say diabetes treatment breakthrough could lead to end of insulin injectionswww.abc.net.auexternal-linkmessage-square9fedilinkarrow-up162arrow-down10file-text
arrow-up162arrow-down1external-linkResearchers say diabetes treatment breakthrough could lead to end of insulin injectionswww.abc.net.aualyaza [they/she]@beehaw.orgM to Science@beehaw.orgEnglish · 11 months agomessage-square9fedilinkfile-text
study in question: EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors
minus-squarefrozen@lemmy.frozeninferno.xyzlinkfedilinkarrow-up7·11 months agoSo they’re repurposing surviving pancreas cells to produce insulin like the destroyed beta cells used to, but what are they doing about the autoimmune response? Will my immune system just kill the new insulin-producing cells as well?
minus-squarebeek@beehaw.orglinkfedilinkarrow-up3·11 months agoPresumably not, since the repurposed cells won’t have the same surface antigens that the immune system targets for destruction.
So they’re repurposing surviving pancreas cells to produce insulin like the destroyed beta cells used to, but what are they doing about the autoimmune response? Will my immune system just kill the new insulin-producing cells as well?
Presumably not, since the repurposed cells won’t have the same surface antigens that the immune system targets for destruction.