I mean what’s more important to you, being able drop the info about time zones when scheduling international meetings, or preserving humanities ability to communicate time respectively to the actual time of day?
I’ve lived in three countries so far and never actually had trouble scheduling anything. The concept of time of day on the other hand is pretty prevalent in my daily life.
That is entirely dependend on the substance, the original addiction, and the individual. Might it lead to a negative spirale? Sure. Addiction is destructive. Depending on the context pretty much anything can be done or consumed to the point of self harm. Probably don’t get into one on purpose like, a general rule of thumb.