It uncovered eight WHO panelists involved with assessing safe levels of aspartame consumption who are beverage industry consultants who currently or previously worked with the alleged Coke front group, International Life Sciences Institute (Ilsi).

Their involvement in developing intake guidelines represents “an obvious conflict of interest”, said Gary Ruskin, US Right-To-Know’s executive director. “Because of this conflict of interest, [the daily intake] conclusions about aspartame are not credible, and the public should not rely on them,” he added.

  • Neato@kbin.social
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    1 year ago

    We’ve studied this chemical literally more than any other food additive and there’s still nothing definitive. Also mice are not a good stand-in for humans. They are really only used for acute toxicity and such.

    • PreachHard@mander.xyz
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      1 year ago

      My gripe is that swapping out sugars for fake ones doesn’t seem healthy long term regardless of any direct impact aspartame itself may have. Just have less sugar imo.

      Edit: didn’t realise how controversial that soft opinion would be lol. Look, drink what you want but I’m going to stick with water unless it’s a treat. I know it’s not healthy for me to scratch the dopamine itch with sugary tasting treats all the time; fake sugar or not. My perspective is less about trying to say, diet soda is bad but that there must be better alternatives to suggest than just sweetener filled copies?

      • zagaberoo@beehaw.org
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        1 year ago

        How do you mean?

        I’ve heard of things like the sensation of sweetness being decoupled from satiation leading to a greater urge for sweetness in compensation, but at least personally that’s not happening to me lol.

        • Rowsdower@lemmy.ca
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          1 year ago

          I think what they mean is we shouldn’t encourage people to drink what is essentially candy water. Doesn’t matter if it has sugar or aspartame. It’s still candy

          Replacing an unhealthy habit with a less unhealthy habit is still unhealthy (written as I drink a Dr Pepper zero)

          • zagaberoo@beehaw.org
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            1 year ago

            Why not though? The health impact of moderate diet soda consumption seems to be pretty negligible.

            • Rowsdower@lemmy.ca
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              1 year ago

              Diet sodas still aren’t water, and they are pretty acidic. They eat away at your teeth, and aren’t great at actually hydrating you. It significantly reduces the harm from drinking candy water, but it doesn’t eliminate them

        • PreachHard@mander.xyz
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          1 year ago

          It’s pretty acidic which sucks for your teeth for one but that wasn’t what I was trying to say

          Yeah I just really mean as a diet as a whole though. If you have an issue with sugar intake then you’re probs drinking way too much sugary drinks. To suggest just swapping out sugars for fake ones I don’t think is best choice to suggest for most people.

          I think there’s probably tons of other issues too just aside from the excess glucose. So fix the diet not the sugar.

          Yeah I agree it’s fine that a most of these chemicals are safe in moderation and well researched. My gripe is the hot swap fix-all attitude that people can take from it.

          • zagaberoo@beehaw.org
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            1 year ago

            That makes sense. I’m coming at this as someone who drinks diet coke because they like it rather than to avoid drinking sugar.

            Amusingly it’s the fact that diet coke is relatively less sweet that makes me like it.

        • Swedneck@discuss.tchncs.de
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          1 year ago

          And even if it’s true, it means you’ll eat the sugar instead of drinking it, and then you’ll be able to ingest less sugar before feeling full, plus you probably get some fibre with it as well which helps a lot.

    • Kingofthezyx@lemm.ee
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      1 year ago

      That’s not what this is saying. This is saying the studies saying it IS harmful were real, and the part saying “it’s probably safe in small amounts” was industry-influenced.

      • cobra89@beehaw.org
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        1 year ago

        No, this is just saying the safe dosage level was biased by people from the industry being on that particular panel.

        Despite the IARC’s new designation, the Joint FAO-WHO Expert Committee on Food Additives (JECFA), which determines safe doses of food additives, did not change its recommendation for daily intake of aspartame. JECFA still says that consuming 40 milligrams of aspartame per every 1 kilogram of body weight (about 2.2 pounds) per day is acceptable, according to a news release.

        This is just 1 panel that determined the safe dosage level. This does not affect the findings of the study at all which concluded that aspartame is “possibly carcinogenic to humans” but that “We don’t know enough about the possible link between aspartame and cancer, but we can’t ignore that there’s something going on”

        So they haven’t even found a definitive link or even said it’s definitively dangerous. And the 40 milligrams per 1 kilogram of body weight is the same as the recommendation from the FDA.

        Also the thing it is replacing, sugar, IS known to cause cancer, diabetes, and other diseases. So take that as you will.

        • CanadianCorhen@lemmy.ca
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          1 year ago

          That last bit is what people always seem to miss.

          Getting hit in the head with a branch is bad for you, but it’s less bad for you than a bullet.

          In the end, you need to compare the two risks, and not decide “a is bad, no need to look at b”

  • no banana @lemmy.world
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    1 year ago

    Literally every fucking health org has studied the chemical and found no evidence of health issues connected to it. It’s only this one study that the IARC cites. And IARC doesn’t take dosage into account either.

    Regardless of people’s taste for aspartame, it is literally not dangerous. It does taste dry. It doesn’t taste like sugar. You do not have to enjoy it. But it is not bad for you.

    edit: my badly worded comment got some discussion going which is great. I just want to say that I was being as hyperbolic as the worried people and I’m sorry. Of course it’s not black or white. There are factors to consider, but what I was trying to express was that aspartame leans to the safe side rather than dangerous.

    Obviously do not drink 25 cans of soda a day, obviously do not compensate for the fact that you’re drinking a “light” product by consuming more of it. But a can a day isn’t gonna ruin your health.

    • phil_m@lemmy.ml
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      1 year ago

      You can almost never say that something is not dangerous, unless it’s practically mathematically proven…

      This applies especially for food etc.

      I think we have to be much more conservative with food and substances we put into it. A lot of (Meta-)meta-studies suggest, that processed food is a health risk.

      And this may sound a little bit far-fetched, but I think a good amount of the idiocracy in (especially) the USA may be related to the food (as also a lot of studies have found connections to brain/psychological health).

      • Cyrus Draegur@lemm.ee
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        1 year ago

        Yeah, actually.

        And, like, literally EVERYTHING has an LD50 value.

        For some things, the value is astronomically gargantuan, though.

        Like, if you have to consume more than your body weight of a substance within thirty minutes in order for it to have a lethal effect, it’s very improbable to ever happen by accident, and very difficult to make happen on purpose.

        Allegedly, the LD50 for aspartame is 10,000 mg per kg of body weight
        (I fucked up the math on the line that used to be here and got justly called out for it; 10,000 mg is only 10 grams. If someone weighs 60kg it would only be 600 grams which is still A LOT but not nearly what I thought it said at first) (And that’s how much to get to a fifty percent chance of dying - I don’t know what the shape of the curve was leading up to this point, it could be nonlinear.) HOWEVER, I can’t recall if LD50 only accounts for acute mortality, or if it also accounts for chronic mortality; like, if it gives you a type of cancer that takes 20 years to kill you somehow, is that even known? no idea.

        • phil_m@lemmy.ml
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          1 year ago

          Additionally to what the others already said:

          LD50 and “bad for your health” are quite separate things.

          Vitamin D for example has an LD50 of ~30mg per kg. So according to your logic, it’s way unhealthier than aspartame (factor ~100). Though in reality you would die without vitamin D intake.

        • Psyblader@feddit.de
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          1 year ago

          10,000 mg equals 10 g, not 10 kg, so you would only need 1/100 of your body weight. Still an unrealistic amount, but far away from 10x.

    • SnowdenHeroOfOurTime@unilem.org
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      1 year ago

      Except for the fact that a decade ago aspartame was shown to create pre-diabetic conditions in the gut, like sugar, except worse. And that studies proved that because psychologically people think it’s “light” they drink more soda and actually gain weight. Yeah if you ignore those pesky little facts it’s totally is 100% harmless. So definitely go around telling people it’s 100% harmless.

      Do you have stock in diet Coke or what?

  • argv_minus_one@beehaw.org
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    1 year ago

    Okay, so, let me get this straight. This panel said aspartame is safe, but it’s got a conflict of interest, so we should ignore all that and fall back to the conventional wisdom that…aspartame is safe?

  • UlyssesT [he/him]@hexbear.net
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    1 year ago

    (chemical in consumer product) is made of SCIENCE therefore it is OBJECTIVELY GOOD and if you have issues with that chemical you must be a TREE HUGGING CRYSTAL HEALING HIPPIE! very-intelligent

    Heard that sort of shit about glyphosate too, especially on reddit-logo

    • Silverseren@kbin.social
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      1 year ago

      I’m sorry that people actually knowing biochemistry is such a problem for you.

      Question: How can a dipeptide of two common amino acids, phenylalanine and aspartic acid, that dissociate in your stomach cause negative health impacts?

      • ඞmir@lemmy.ml
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        1 year ago

        Everything has a negative health impact, literally even water does. The question is always about cumulative and spontaneous dosage. At what point does it become bad for you.

        One common explanation I’ve seen for aspartame is that it makes your body think you’re drinking sugar while no sugar is being absorbed. This is then potentially harmful for those with a predisposition for diabetes.

        • Silverseren@kbin.social
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          1 year ago

          That is a known effect, yes. And an understandable one that occurs just because of the sweet receptor response. But that has nothing to do with the effects being claimed by others about it.

          • ඞmir@lemmy.ml
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            1 year ago

            It’s possible that the increased risk of diabetes snowballs into an increased risk of cancer from diabetes’ secondary conditions. Making claims about “these amino acids are harmless so the substance is harmless” disregards the possible chains of events that could actually cause more conditions.

            • Silverseren@kbin.social
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              1 year ago

              That is something that can be researched and would apply to anything that tastes sweet, of course, if true. But that’s still not the things being claimed by people about the impacts aspartame is having on them.

              Essentially, they’re making claims akin to the MSG conspiracies, with the same lack of evidence for anything. Including with placebo studies showing the people claiming these effects also claiming it when they think they’re consuming the substance, but they aren’t.

  • Silverseren@kbin.social
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    1 year ago

    Okay, corruption like that should be corrected. Regardless, there’s no scientific evidence that aspartame is harmful. Let alone a biochemical reason for why a dipeptide of two amino acids, phenylalanine and aspartic acid, that dissociates in the stomach into its constituent components and some byproducts would be harmful in the first place.

    Unless you have phenylketonuria, but you have much bigger problems in that case and, if that is the case for you, kudos on being at an age and capability to read and understand this post, you are incredible.

    Edit: Also, just noticed the part about US Right To Know, which is a well known anti-science group that’s been pushing pseudoscience and fearmongering about other topics, such as biotechnology, for years. So them being involved here raises questions.

      • Silverseren@kbin.social
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        1 year ago

        Then drink the Diet Coke with Splenda one? There’s also Coke Life that has stevia instead. They basically made sure they have a version with each type of sweetener.

          • Sassy@lemm.ee
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            1 year ago

            Fuck yes. Why is there sugar added to applesauce and fruit juice? Why is it so hard to find low calorie drinks that don’t contain artificial sweeteners? The way to curb sugar intake is moderation.

            • Myrhial@discuss.online
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              1 year ago

              Sugar is antibacterial, hence why honey can stay good like forever. It’s a cheap way to increase shelf life that also makes people really like the food because we evolutionary seek that stuff out. It’s not right though. We work long hours so convenient foods should allow us to buy back some time. But when they’re all like this, you end up either having to do it yourself or risk your health. There should absolutely be limits. But with food costs as they are, who is going to fight for that? The alternatives are more expensive, or you reduce shelf life. It’s much better regulated here in the EU but we too are still not there, obesity is still on the rise.

              • oce 🐆@jlai.lu
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                1 year ago

                It’s tasty, cheap, antibacterial and gives attractive colors (caramel). That’s why companies like to put it everywhere, it’s just awfully convenient.

  • shiveyarbles@beehaw.org
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    1 year ago

    A lot of strange defending of this corrupt behavior here. The fact that this corruption exists immediately calls into question the safety of the recommendations. It won’t be the first time Americans were killed for corporate profits.

    • Silverseren@kbin.social
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      1 year ago

      A lot of scientists who actually know the studies and biochemistry involved, actually. Not “defending of this corrupt behavior”, but just pointing out that corrupt behavior doesn’t negate the science itself.

      Corruption is a part of companies and capitalism. Even the “good” companies, like renewables, are corrupt and do corrupt things.